1.开发医用高分子、无机纳米颗粒、功能多肽等生物医用材料 

2.探索免疫治疗、光热治疗、光动力治疗和化疗等新型联合干预策略

3.开展抗肿瘤、抗菌、皮肤修复、心血管疾病、肾脏疾病等相关领域的应用

1. Liu Q, Chen X, Jiang Y, Yan M, Yu B, Zhang W, Cen Y, Zhang JY, Zhang J, Lei Q*, Li SY*, Yang B*. Self‐Promoted Targeting Delivery of Nanodrug Through Chemotherapeutic Upregulation of CD47 for Triple Negative Breast Cancer Therapy. Advanced Functional Materials 2024, 34 (13), 2311677.

2. Liu Q, Liang J, Gu Y, Gao H, Yang D, Jiang Y, Zhang J, Lei Q*, Yang B*. CD47-targeted liposomal chemotherapy upregulates CD47 expression and induces microsatellite instability which enhances cancer immunotherapy. Journal of Controlled Release 2025, 388, 114351.

3. Li YW, Duan YX, Li YY, Gu Y, Zhou L, Xiao ZT, Yu XY, Cai YJ, Cheng EZ, Liu QQ, Jiang Y, Yang Q, Zhang F*, Lei Q*, Yang B*. Cascade loop of ferroptosis induction and immunotherapy based on metal-phenolic networks for combined therapy of colorectal cancer. Exploration 2025, 5(1), 20230117.

4. Duan Y, Gu Y, Liang J, Li N, Huang H, Li Y, Shah BA, Liu Y*, Yang B*. Enhancing immunotherapy in colorectal cancer by immune-modulatory and lipid-metabolism reprogramming with host-guest co-delivery nanoplatform. Chemical Engineering Journal 2026, 527, 171861.

5. He PY, Lei Q, Yang B*, Shang TY, Shi JJ, Ouyang Q, Wang W, Xue LC, Kong FH, Li ZY, Huang JD, Liu LH, Guo JM, Brinker CJ, Liu KS*, Zhu W*. Dual-Stage irradiation of size-switchable albumin nanocluster for cascaded tumor enhanced penetration and photothermal therapy. ACS Nano 2022, 16(9), 13919-13932.

6. Deng FA, Yan MY, Liu YB, Wang RX, He HQ, Chen AL, Wang JJ, Xu L, Yang B*, Cheng H*, Li SY*. Self-delivery of metal-coordinated mitochondria protonophore uncoupler for O2-exhausting enhanced bioreductive therapy. Biomaterials 2022, 286, 121576.

7. Huang J#, Yang B#, Peng Y, Huang JS, Wong SHD, Bian LM, Zhu KS*, Shuai XT*, Han SS*. Nanomedicine-Boosting Tumor Immunogenicity for Enhanced Immunotherapy. Advanced Functional Materials 2021, 31(21), 2011171.

8. Li Z, Guo S, Cao KX, Duan YX, Zhao Y, Chen YX, Li ZL, Huang SQ, Song MC, Wang CL, Zhang YT, Yu SH, Bai ZX, He J*, Yang B*, Xu YM*. Endothelial monocarboxylate transporter 1 drives atherosclerosis via a lactate/NADH/CtBP-mediated transrepression pathway. MedComm 2025, 6(2), e70089.

9. Cai Y, Jiang Y, Chen Y, Cheng E, Gu Y, Li Y, Liu Q, Zhang J, Liu J*, Han S*, Yang B*. Amplifying STING activation and immunogenic cell death by metal-polyphenol coordinated nanomedicines for enhanced cancer immunotherapy. Chinese Chemical Letters 2025, 36(5),110437.

10. Shang T, Yu X, Gu Y, Du R, Cai YJ, Li YW, Zheng GD, Wang CQ, Zhang J, Liu JF*, Han SS*, Yang B*. Supermolecular nanovehicles co-delivering TLR7/8-agonist and anti-CD47 siRNA for enhanced tumor immunotherapy. International Journal of Biological Macromolecules 2023, 251, 126539.